How To Treat Bunions
March 29, 2013 – 12:00 am | No Comment
A bunion is a deformity that is mainly made up of a lateral deviation of the great toe which enlarges due to a tissue or a bone. It is a serious foot problem. These are formed within the foot and not on the surface of the foot. An arthritic condition and  a result of bone degeneration it is found as  a lump on the outside portion of the big toe. Bunions are seen near the joint of the toe and sometimes  [...]

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Novel Drug Targets Cancer Stem Cells

Submitted by on August 16, 2009 – 9:11 pmOne Comment



U.S. researchers have unravelled a new-fangled approach wherein a compound has been discovered that targets specific master cells that aid in the proliferation of breast cancer cells.

The study conducted on mice involved the use of the drug salinomycin, a farm-derived antibiotic that exterminated breast cancer cells and retarded tumour escalation with far greater precision than several of the existent drugs.

Many UK experts have cautioned that the parallel adaptation on humans would take a few years. A dubious reasoning as to the persistent recurrence of some cancers despite strong chemotherapy sessions has left scientists baffled.

Many researchers have derived a conclusion that stem cells that are capable of being resistant to chemotherapy play a crucial role in seeding new tumours and boosting their numbers.

The scientists at Massachusetts Institute of Technology have after doing a laboratory trial of 16,000 existent chemical compounds on breast cancer cells have realized the bright prospects of the drug Salinomycin. Those compounds that displayed optimal results were subsequently experimented on mice and its performance gauged against prevalent drugs like paclitaxel.

Salinomycin outperformed other drugs by being hundred times more effective at destroying the cells in a test tube and those mice cells after being injected by the drug were less prone to starting new tumours and retarded growth of existent tumours.

Professor Eric Lander from MIT was optimistic that this discovery would be a harbinger for future novel cancer-busting treatments. Though he added that in several therapies known to kill the bulkiness of a tumour, their relapse is imminent in most cases.

Dr.John Stingl, group leading the batch in mammary system cell biology at the Cancer Research UK’s Cambridge Research Institute has pegged this research to being the biggest noted in this year, adding that the true test is the future inculcation of  these range of drugs to the clinics to be effectively tried on patients with positive results.

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