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A pregnant woman usually undergoes many changes and the typical waddle is a major feature of a pregnant woman’s life. Investigators have seen that the women walk the same way even after they deliver thus affecting the bones, joints, and muscles. The changes in the overall distribution and body mass are something that should not be left unattended. This is what results in major changes in the physiological  [...]

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Needle-free Therapies: Boon for Multiple Sclerosis Sufferers

Submitted by on January 25, 2010 – 12:45 amNo Comment




Multiple Sclerosis (MS) is a complex, chronic and frequently immobilizing ailment varying amongst those inflicted by it. The pill-version treatment for multiple sclerosis is soon to brace reality and a notable advancement in this area. The choice of going in for pills rather than needles is definitely a welcome change for all those individuals presently having the option of needle-only MS treatments.

The presently obtainable prospective 5 first-in-line disease-modifying treatments initially started being available nearly two decades back. Four of these therapies are injections, varying in administration from being offered a single instance in a day or once in seven days. A number of years back, Tysabri drug was unveiled that offered a novel choice for MS-inflicted individuals as it was administered via intravenous route once in every 4 weeks time. These disease-modifying drugs are aimed at reducing the occurrence, severe nature of the attacks and slacken the advancement of the condition. Based on the treatment, clinical reoccurrences could be lowered by anywhere in-between one-thirds and two-thirds.

Three new-fangled trials that were lately printed in the New England Journal of Medicine are quite heartening news for more than four lakh individuals in the United States and above 2 million MS-inflicted globally having this incapacitating neurological disease. The outcomes of the clinical studies that would particularly benefit those individuals having relapsing-remitting MS show 2 medications cladribine and fingolimod appearing to be immensely useful in combating the ailment. Both of these medications have apparently analogous benefits, namely reducing recurrence rates, the likelihood of slowing the rate at which disability progresses and reducing perceivable Multiple sclerosis activity in the brain when viewed on Magnetic Resonance Imaging or MRI scanning. The additional advantage is that these two drugs are to be taken orally.

As both of these medications have an effect on the immune system, augmented rates of infection were observed in those individuals that took these drugs in comparison to those people in the placebo group. Researchers are continuing to keep close vigil on the rate of cancer for ascertaining whether these medicines are associated with greater rates.

Dr. John Richert, Exec- VP, National Multiple Sclerosis Society has stated that the side effects seem to be vastly controllable. He however mentioned that it would be imperative for drug-manufacturers for setting up long-standing follow-up trials as a means of supervision.

This vastly convenient option of therapy could be helpful in prompting patients in starting treatment early on and for staying on their medicines for protracted time periods – both of which are decisive in fighting the disease.

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