How To Treat Bunions
March 29, 2013 – 12:00 am | No Comment
A bunion is a deformity that is mainly made up of a lateral deviation of the great toe which enlarges due to a tissue or a bone. It is a serious foot problem. These are formed within the foot and not on the surface of the foot. An arthritic condition and  a result of bone degeneration it is found as  a lump on the outside portion of the big toe. Bunions are seen near the joint of the toe and sometimes  [...]

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Home » Breakthrough in science

Immune Suppression Hinders Cancer Treatments

Submitted by on November 9, 2010 – 5:39 amNo Comment



The researches for cancer treatments are under revolution. The reasons behind the failures pertaining to the previous researches in the field of cancer and its treatments have been discovered. They have all landed back to the insides of the human body. Researchers say that the thing that ceases the immune system to participate in the treatment of tumors lies within the body itself. They are special kinds of cells in the stromal cells or cancer cells. A type of these cells, of the connective tissue of body organs, releases the fibroblast activation protein (FAP) alpha. This protein averts the immune system from responding back towards the cancer tumors in the body. These cells are present within the tumor itself. The adversity of the presence of these cells is that they restrict the effects of vaccinations and other therapies that are most partly relied on the immune system functioning of the body. Researchers have found a way out by destroying these cells in the tumor. This shall relieve the suppression of the immunity against the tumor terrors.

The experts of Immunology at the University of Cambridge, Douglas Fearon and Sheila Joan Smith, state that a cancerous tumor is a complex mixture of cells. Finding the specific cells that need to be destroyed to bring rejuvenation to the immune system is an essentially great step. Due to the prevalence of these cells in the tumors, the vaccinations, which are developed and injected in the body for triggering the immune system to act against these cells, also do not show any effects. As a result, these tumors are always seen to grow and the suppressing therapies fail.

The tumor structure is a microenvironment in which the immune cells are suppressed and, hence, refrain from being active and preventing the hazardous business of the tumors. This is the main reason for therapists being unable and unsuccessful in reversing the immune suppression completely.  According to the Cambridge studies, the findings are that at least one of all the components that cause the suppression of the immune system is contained inside every cell of the normal tissue – the stromal cells. This aids the cancer to intimidate the immune and suppress it to realize its existence and growth even greatly. It is hoped that the new researches in the world of cancer do live up to the expectations of the patients and the doctors in reversing the immune suppression, thus, aiding the cancer elimination from the body.

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