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Blood Pressure Medications Helpful for Some People with Normal BP

Submitted by on March 2, 2011 – 12:55 amNo Comment




A methodical examination of medical proof indicates individuals that experienced strokes or heart attacks may be benefited by the use of blood pressure medications, although when they have normal BP (blood pressure).

Scientists noted that from each one thousand individuals who took the medications in scientific studies; typically there were fifteen lesser deaths due to heart diseases as compared to when the patients received placebo therapy.

However, the novel trial appearing in the ‘Journal of the American Medical Assn.’ could not extract the reason for this & specialists state that it is quite early to amend therapy advice.

Doctor L. Bazzano from Tulane Univ., N. Orleans, the lead researcher stated that their team isn’t supporting placing one & all on such blood pressure medications as there are plentiful well-established side-effects. For this reason she believes it is crucial to promptly seek medical advice on whether the advantages would be outweighing the risks for that particular patient.

Around 1/3rd of adults from the U.S. have hypertension (high blood pressure) which is deemed a heart disease risk factor. Heart disease is the principal slayer globally & causal to around one-third of all mortalities in the United States.

Parameters presently recommend lifestyle amendments like weight loss & restricting sodium for hypertension patients. In case these measures fail, physicians might then be trying with medications like diuretics (water pill), angiotensin-converting enzyme (ACE) inhibitors or beta blocker drugs.

What’s yet debatable, though, is whether such medications even help individuals whose BP has not touched the cut-off mark of 140 by ninety.

The study group did a pooling of twenty-five past trials that comprised of over sixty-four thousand patients having a past of heart attacks, strokes or cardiac failures, though sans hypertension.

Trial entrants were in their fifties or sixties & a follow-up done on them till around 5 years. They were given blood pressure medications – for example, ACE inhibitor, CCB, beta blocker drugs or a placebo pill.

Across the panel, the medications were associated to plummets in heart disease & mortality. For each one thousand individuals taking them, for instance, there were 8 lesser cases of stroke, thirteen lesser heart attack cases, forty-four lesser heart failure cases & fourteen lesser mortalities on the whole.

The novel outcomes reveal that individuals having heart disease might be benefited from hypertension drugs irrespective of their BP.

However, specialists are still not suggesting the medications prior to further trials being conducted. The trial team stated that hypertension therapy can be costing amid fifty & 1000 dollars yearly, based on the medications deployed.

Some specialists state that beta blocker & ACE inhibitor medications have been suggested for survivors of heart attacks or having cardiac failures – not since they lowered BP, though due to their shielding effect on the heart. Accupril & Tenormin are commonly used drugs.

Some sceptics’ state that since the novel examination is pooling in past trials of diverse medications it is not clear what part certain medications don. An assumption of them all working isn’t justified. Some even point of the blockers not being properly tolerated & causing depression, weariness, nightmare & impotence.

Also a viewpoint in the medical journal even appears to be striking a wary message that since several patients might potentially commence intake of medicines at younger age & for protracted periods of time for preventing heart episodes, even moderate expenses & unfavourable effects need to be taken into consideration.

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